2024 Rome, Italy

I-73 Ioannis Loisios-Konstantinidis
Combining physiologically based pharmacokinetic modeling and simulations and allometry to inform the starting dose of asciminib in pediatric patients
Wednesday 10:00-11:30
I-79 Belén Pérez Solans
Pharmacokinetic analysis across studies to drive knowledge-integration: optimal dose finding of rifampicin for the treatment of drug-susceptible tuberculosis in children
Wednesday 10:00-11:30
I-80 Soumya Perinparajah
Modelling the pharmacodynamics of rituximab biosimilar in children with rheumatological conditions
Wednesday 10:00-11:30
I-81 Anne Ravix
Dosing optimization of amoxicillin in children treated for Lyme disease
Wednesday 10:00-11:30
I-82 Leyanis Rodriguez Vera
Showcasing the potential of PBPK modeling to inform drug-drug interactions specific recommendations for pediatric labeling: omeprazol case example
Wednesday 10:00-11:30
I-84 Stephan Schaller
Using PBPK Modeling to support an adaptive “First-in-Pediatric” trial design of Sonlicromanol for the treatment of Primary Mitochondrial Disease
Wednesday 10:00-11:30
I-85 Maja Skataric
Dabrafenib and Trametinib dose optimization in 6-17 year old tumor agnostic patients based on established efficacy surrogate targets in adults
Wednesday 10:00-11:30
I-86 Melina Steichert
Enalapril orodispersible minitablets for pediatric heart failure - a population pharmacokinetic analysis from multicenter Phase II/III LENA clinical trials
Wednesday 10:00-11:30
I-87 Mita Thapar
Population pharmacokinetic and exposure-response analysis for ambrisentan for the treatment of pulmonary arterial hypertension in paediatric subjects aged 8 to less than 18 years.
Wednesday 10:00-11:30
I-90 Lufina Tsirizani
Population pharmacokinetics of ritonavir-boosted darunavir in children aged 3 to 15 years in the CHAPAS 4 trial living with HIV in Africa.
Wednesday 10:00-11:30
II-98 Jen-Hao (Eric) Wu
Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory Acute Lymphoblastic Leukemia – results of study ITCC-059
Wednesday 15:35-17:00
III-05 Fan Cheng
Favipiravir pharmacokinetics in immunocompromised infants and children with chronic RNA viral infections
Thursday 10:15-11:45
III-06 S. Y. Amy Cheung
Predicting RSV prophylaxis in the infant target population – assessing monoclonal antibody versus maternal vaccination efficacy using MBMA
Thursday 10:15-11:45
III-07 Marc Codaccioni
Predictive performance of two hepatic CYP3A4 ontogeny within a paediatric PBPK model.
Thursday 10:15-11:45
III-08 Alessandro Di Deo
A model-based algorithm for mycophenolate dose adjustment in paediatric transplantation patients
Thursday 10:15-11:45
III-11 Klervi GOLHEN
Characterizing effect of methotrexate on adalimumab PK in pediatric patients with inflammatory rheumatic disease
Thursday 10:15-11:45
III-12 Silvia Grandoni
Efficacy extrapolation and dose rationale for duloxetine in paediatric chronic pain
Thursday 10:15-11:45
III-21 Feras Khalil
A joint parent-metabolite model to characterize the pharmacokinetic profile of tapentadol and its metabolites in the pediatric population and inform a model-based evaluation of a post-approval commitment pediatric trial
Thursday 10:15-11:45
III-34 Xia Li
Model Informed Dose Evaluation for Aticaprant in Adolescent Patients Following the Adult Dose Regimen
Thursday 10:15-11:45
III-91 Anne van Rongen
Quantification of renal drug clearance in neonates born Small for Gestational Age (SGA) compared to neonates born Appropriate for Gestational Age (AGA)
Thursday 10:15-11:45
III-93 Yunjiao Wu
When will the glomerular filtration rate in preterm neonates catch up to their term peers?
Thursday 10:15-11:45